2-Methoxyethanol: Properties, Uses, and Safety Precautions

2-Methoxyethanol, also known as methyl cellosolve, is an organic solvent commonly used in industrial and laboratory applications. It is a colorless, volatile liquid with a mild, sweet odor and is known for its excellent solvent properties. Due to its potential health hazards, proper handling and safety measures are essential.

Chemical Properties

• Chemical Formula: C₃H₈O₂
• Molecular Weight: 76.09 g/mol
• Boiling Point: ~124°C (255°F)
• Density: 0.96 g/cm³
• Solubility: Completely miscible with water and most organic solvents
• Flammability: Flammable liquid with a flash point of ~40°C

Applications of 2-Methoxyethanol

1. Industrial Solvent – Used in the paint, coatings, and ink industries due to its ability to dissolve resins and dyes.
2. Electronics Industry – Utilized in semiconductor processing and circuit board manufacturing.
3. Chemical Synthesis – Serves as a reaction medium in pharmaceutical and agrochemical production.
4. Cleaning Agent – Found in industrial degreasers and metal cleaners.
5.  
6. Plastic & Polymer Industry – Used in plasticizers and adhesive formulations.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAA4460 in the slot below. This is an example certificate only and may not be the lot that you receive.

Health & Safety Hazards

Toxicity Concerns: 2-Methoxyethanol is harmful if inhaled, ingested, or absorbed through the skin.

Proper Handling & Storage:
    Use Protective Equipment – Wear gloves, goggles, and lab coats when handling.
    Ventilation – Work in a well-ventilated area or use fume hoods to reduce exposure.
    Proper Storage – Store in a cool, dry place, away from oxidizing agents.

Regulatory Status

Many countries restrict or regulate the use of 2-Methoxyethanol due to its health risks. Always check local regulations before using this chemical in industrial applications.

Conclusion

2-Methoxyethanol is a versatile but hazardous solvent widely used in industries such as electronics, coatings, and chemical manufacturing. While it offers excellent solvent properties, its toxicity and flammability make proper handling and safety precautions essential.

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